{"id":659,"date":"2020-12-11T05:40:06","date_gmt":"2020-12-11T00:40:06","guid":{"rendered":"https:\/\/longevityomics.com\/?post_type=news_publication&#038;p=659"},"modified":"2021-01-31T01:21:13","modified_gmt":"2021-01-30T20:21:13","slug":"integrative-longevity-omics-ilo-study-pursuing-the-role-of-gut-bacteria-in-exceptional-longevity","status":"publish","type":"news_publication","link":"https:\/\/longevityomics.org\/es\/news_publication\/integrative-longevity-omics-ilo-study-pursuing-the-role-of-gut-bacteria-in-exceptional-longevity\/","title":{"rendered":"Estudio Omics Integrativas de Longevidad (ILO) que analiza el papel de las bacterias intestinales en la longevidad excepcional"},"content":{"rendered":"<p>Daniel Segr\u00e8, y su laboratorio se est\u00e1n preparando para analizar los datos del microbioma de los participantes centenarios y descendientes de los centenarios. <\/p>\n\n\n\n<p>En su art\u00edculo de octubre de 2020, los autores describen m\u00e9todos para cuantificar y analizar las muy complejas pero biol\u00f3gicamente potentes redes de organismos que coexisten en nuestros intestinos. Las bacterias en nuestro tracto digestivo sintetizan vitaminas importantes y producen metabolitos, amino\u00e1cidos, \u00e1cidos grasos de cadena corta y otras sustancias que ya se ha demostrado que ejercen una fuerte influencia en nuestro sistema nervioso central e inmunol\u00f3gico y, en general, en el envejecimiento, la salud y la enfermedad. El trabajo cient\u00edfico sugiere que los centenarios y sus descendientes tienen redes de microbiomas que conducen a un envejecimiento m\u00e1s lento y resistencia a las enfermedades relacionadas con el envejecimiento, como el Alzheimer y la enfermedad cerebrovascular. <\/p>\n\n\n\n<p>El art\u00edculo del laboratorio de Segr\u00e8 describe una herramienta de tuber\u00eda que se puede utilizar para integrar m\u00faltiples conjuntos de datos y para generar an\u00e1lisis comparativos y redes de consenso que pueden ayudar a comprender y controlar el ensamblaje de la comunidad microbiana en diferentes biomas.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.09.23.309781v2.full\" style=\"border-radius:50px\">Leer art\u00edculo completo<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\" https:\/\/github.com\/segrelab\/MiCoNE\" style=\"border-radius:50px\">MiCoNE (por sus siglas en ingl\u00e9s)<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>ILO investigator Daniel&nbsp;Segr\u00e8 and his laboratory are gearing up to analyze microbiome data from the ILO centenarian and centenarian offspring participants. In their October 2020 paper, the authors describe methods to quantify and analyze the very complex but biologically potent networks of organisms that co-exist in our guts. 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