Consortium to integrate analyses of the genomic, proteomic, and metabolomic bases of human longevity and the lifespans of animal species into models of the molecular pathways that contribute to human longevity.
LLFS is a unique international project that is studying families who have several of members reaching a very old age.
The overall hypothesis of this study, titled “Resilience/Resistance to AD in Centenarians and Offspring” (RADCO), is that centenarian cognitive superagers and some of their offspring have protective factors that confer such resilience or in some cases, even resistance against cognitive decline and dementia.
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